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Paroxetine Side Effects


Paroxetine, also known by its brand name Paxil, is an antidepressant in the class of drugs known as selective serotonin reuptake inhibitors (SSRI). Paroxetine is used to treat obsessive-compulsive disorder, depression, anxiety disorders, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).

The US Food and Drug Administration first approved paroxetine back in 1992.

Serious Side Effects of Paroxetine

The following presents an extensive but not comprehensive list of potential side effects from taking Paroxetine. It's possible that a patient might not experience any of these side effects, or they may experience one or more. Should any of the following occur, seek medical attention immediately.

  • Allergic reaction (in the form of a rash, hives. Itching, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue)
  • Trouble urinating, or black or bloody stools
  • Decreased concentration or coordination
  • Exaggerated reflexes or Exaggerated feeling of well-being
  • Sweating or fainting
  • Fast or irregular heartbeat
  • Fever, chills, or sore throat
  • Persistent, painful erection
  • Sleeping problems, or weakness
  • Severe nausea, vomiting, diarrhea, or headache
  • Weight loss
  • Suicidal thoughts
  • Unusual bone pain or unexplained swelling, or tenderness
  • Unusual bruising or bleeding
  • Severe mental or mood changes
  • Worsening of depression
  • Persistent or severe ringing in the ears
  • Skin problems (like swollen, blistered, or peeling skin)
  • Vision changes
  • Severe anxiety, agitation, panic attacks, aggressiveness, impulsiveness, hostility, restlessness

Common Side Effects of Paroxetine

The following list is composed of the more commonly experienced side effects of Paroxetine.

  • Trouble sleeping
  • Anxiety or nervousness
  • Decreased sexual desire or ability to achieve orgasm
  • Diarrhea or constipation
  • Drowsiness or dizziness
  • Dry mouth
  • Signs of flu or infection such as fever, chills, muscle aches)
  • Increased urination
  • Excess gas
  • Blurred vision
  • Numbness or tingling of the skin
  • Increased sweating
  • Appetite loss
  • Nausea
  • Upset stomach

Experiencing a side effect while taking any medication might be common, but it is recommended that patients report all side effects to their primary care provider, regardless of the severity.

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