Sponsored Links


Off-label use of antipsychotic drugs may have benefits


Even though atypical antipsychotic medications are commonly used for off-label conditions such as behavioral symptoms of dementia, anxiety, and obsessive-compulsive disorder, these medications are in fact only effective for a few off-label conditions. The benefits and harms of these medications when used off-label vary. The research article is printed in the latest issue of JAMA. With use of off-label drugs increasing the study helped to confirm the use.

Alicia Ruelax Maher MD of RAND and colleagues conducted an examine to see the efficacy and adverse events associates with off-label use of these drugs. They are being used to treat behaviors associated with dementia, anxiety, OCD, eating disorders, post-traumatic stress disorder, insomnia, personality disorders, depression, and substance abuse.

Among the findings, researchers found aripiprazole, olanzapine, and risperidone were associated with small but statistically significant benefits for the treatment in elderly patients of behavioral symptoms of dementia, such as psychosis, mood alterations, and aggression. For generalized anxiety disorder, quetiapine was associated with a 26% increase in the chance of a favorable response over a placebo. For OCD, risperidone was associated with a 4-fold increase in the chance of responding compared with placebo. Substance abuse and eating disorders did not respond to off label use of any drugs.

“The benefits and harms vary among atypical antipsychotic medications for off-label use,” the authors concluded. “This evidence should prove useful for clinicians considering off-label prescribing of atypical antipsychotic medications, and should contribute to optimal treatment decision making for individual patients with specific clinical symptoms and unique risk profiles.”

Source: ScienceDaily, JAMA

call now icon Free Treatment Assessment
Call Now—Help Available 24/7 (877) 331-9311


OCD Self Test

Do you or a loved one feel like you might have a problem with OCD?
Take the Self Test now to get more information.


Sponsored Links



The information provided on brainphysics.com is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her health professional. This information is solely for informational and educational purposes. The publication of this information does not constitute the practice of medicine, and this information does not replace the advice of your physician or other health care provider. Neither the owners or employees of brainphysics.com nor the author(s) of site content take responsibility for any possible consequences from any treatment, procedure, exercise, dietary modification, action or application of medication which results from reading this site. Always speak with your primary health care provider before engaging in any form of self treatment. Click here to read our complete Terms of Use.

Free Treatment Assessment
Call Now—Help Available 24/7 (877) 331-9311

Sign up for our newsletter to receive mental health Information & Inspiration


Sponsored Links

You May Also Want To Read


Other People Are Also Reading


Online Support Groups

visit SupportGroups.com

SupportGroups.com provides a support network for those facing life's challenges. Click on the following links to get a helping hand in a confidential, caring environment.

Support Groups


BrainPhysics.com Social