Sponsored Links


Cancer drug may help treat Alzheimer's


People with Alzheimer’s have nerve cells that contain tangles. These are distorted clumps of protein tau. Normally, tau helps stabilize the microtubules with a cell. They transport nutrients from one end of the cell to the other. It may be that the breakdown of normal tau function causes the microtubules to break down and lead to nerve cell damage for people with Alzheimer’s disease.

Kurt Brunden, PhD, and colleagues treated mice bred to develop Alzheimer’s-like symptoms with EpoD. The drug prevented microtubule breakdown and cognitive difficulties.

For this new study, the treated older mice that had advanced symptoms of Alzheimer’s. These mice already had the tau tangles and memory deficits. The administered EpoD for three months. The EpoD mice, when compared to the untreated mice, had reduced formation of tau tangles in the brain. They also outperformed animals that did not receive the drug.

“These results suggest that EpoD might have therapeutic benefit in Alzheimer’s disease and related neurodegenerative diseases, such as frontotemporal lobar degeneration, where abnormal tau tangles are present,” said Brunden.

EpoD easily crosses the brain barrier unlike other medications. Only a low dose was required and there were no side effects.

“EpoD readily enters the brain, where it appears to persist for a much longer time than in the blood. This may explain why low doses were both effective and safe in the mouse model of Alzheimer’s disease,” explained Brunden.

Source: Society for Neuroscience, MedicalNewsToday

call now icon Free Treatment Assessment
Call Now—Help Available 24/7 (877) 331-9311


OCD Self Test

Do you or a loved one feel like you might have a problem with OCD?
Take the Self Test now to get more information.


Sponsored Links



The information provided on brainphysics.com is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her health professional. This information is solely for informational and educational purposes. The publication of this information does not constitute the practice of medicine, and this information does not replace the advice of your physician or other health care provider. Neither the owners or employees of brainphysics.com nor the author(s) of site content take responsibility for any possible consequences from any treatment, procedure, exercise, dietary modification, action or application of medication which results from reading this site. Always speak with your primary health care provider before engaging in any form of self treatment. Click here to read our complete Terms of Use.

Free Treatment Assessment
Call Now—Help Available 24/7 (877) 331-9311

Sign up for our newsletter to receive mental health Information & Inspiration


Sponsored Links

You May Also Want To Read


Other People Are Also Reading


Online Support Groups

visit SupportGroups.com

SupportGroups.com provides a support network for those facing life's challenges. Click on the following links to get a helping hand in a confidential, caring environment.

Support Groups


BrainPhysics.com Social