A new study has found that there may be a link between poor oral hygiene and Alzheimer’s disease.
Researchers from the University of Central Lancashire (UCLan) in the UK have discovered the presence of a bacterium called Porphyromonas gingivalis in the brains of living patients with dementia and Alzheimer’s disease. The bacterium is associated with chronic periodontal, or gum, disease.
Immune response may kill neurons
This particular bacterium is found in oral cavities and enters the blood stream through a variety of routine activities like chewing and brushing the teeth. However, it is more likely to enter the blood stream after invasive dental treatment.
Each time the bacteria travel to the brain, researchers believe they may trigger immune system responses that can cause the release of excess chemicals that kill neurons. The destruction of the neurons could lead to confusion and deteriorating memory, which are typical symptoms of Alzheimer’s.
Supports other findings
Other research has led in this direction as well. Research from NYU in 2010 showed long-term evidence that linked gum inflammation and Alzheimer’s. Gum disease could increase risk of cognitive dysfunction. Another study from the University of New Mexico suggests herpes simplex virus type 1 may also be connected to Alzheimer’s.
“Whereas previous studies have indicated a link between dementia and other bacteria and viruses such as the Herpes simplex virus type 1, this new research indicates a possible association between gum disease and individuals who may be susceptible to developing Alzheimer’s disease, if exposed to the appropriate trigger,” stated professor St. John Crean from the School of Medical Dentistry at UCLan.
Source: MedicalNewsToday, Journal of Alzheimer’s Disease
